Contract Research Blog | Preclinical Oncology Research Blog

PDX models are a critical type of preclinical model used in cancer research. In PDX models, cancerous tumor tissue from a human patient is implanted into immunodeficient mice or other host animals. The implanted tumor is then allowed to grow in the host, providing researchers with a model system to study tumor growth, metastasis, and response to potential therapies.

A mouse model is a research methodology where mice are used as experimental subjects to study biological phenomena, investigate diseases, and develop treatments. Mice are often used as a model organism because they share many physiological and genetic similarities with humans

A xenograft is a clinical or research procedure where soft tissue or organ material is transplanted from one species into a different species. In clinical medicine, xenografts have been used in certain cases where human tissue or organs are not readily available for transplantation. Xenografts can also be used in medical research to study the function and behavior of various tissues and organs, as well as to develop new treatments and therapies for diseases.