Clinical Testing Services

LIDE does not offer clinical testing services but offers several preclinical services that will optimize your clinical trials:

  • Indication screens using genetically modified or drug resistant models
  • Biomarker identification to guide patient stratification and recruitment strategy

Traditional oncology clinical trials are either basket trials or umbrella trials. 

  • Basket trials test multiple tumors with similar molecular abnormalities, to identify the best indications for treatment.
  • Umbrella trials test a single tumor type but different molecular biomarkers, to identify best responders.

LIDE’s Functional Diagnosis platform offers complementary insights as basket and umbrella trials, prior to the clinical trial phase:

  • MiniPDX Mouse Trial – fast, cost-effective drug screens with similar predictive power as traditional PDX 
  • OMICS analysis – identifying biomarkers through advanced bioinformatics analysis at all levels of transcription

 

Fig. LIDE Functional Diagnosis platform can offer complementary insights to basket and umbrella trials but in preclinical stage.

Fig. LIDE Functional Diagnosis platform can offer complementary insights to basket and umbrella trials but in preclinical stage.