LIDE has established 1700+ PDX models. WES and RNAseq profiling, including IHC, has confirmed PDX models with different expression profiles for popular targets like ADC, CAR-T, etc. Many of these have matching cell lines to support complementary in-vitro studies. Please reference partial list below but contact us for the most updated.
| Expression/mutation | Cell line | Cancer | Expression/mutation | Cell line | Cancer |
| Claudin18.2 high expression | OE19 | Esophageal cancer | LRRC15 high expression | U-87 MG | Brain astrolastoma |
| NUGC4 | Gastric cancer | U-118 MG | Astroblastoma | ||
| KATO III | Gastric cancer | 143B | Osteosarcoma | ||
| TROP2 high expression | A172 | Glioblastoma | MG-63 | Osteosarcoma | |
| LN-229 | Brain medulloblastoma | Saos-2 | Osteosarcoma | ||
| U-87 MG | Brain astroblastoma | HER2 high expression | OE19 | Esophageal cancer | |
| MKN28 | Gastric cancer | SK-BR-3 | Breast cancer | ||
| MKN45 | Gastric cancer | KRAS G12C | MIA PACA-2 | Pancreatic cancer | |
| ERBB3 high expression | Hep G2 | Liver cancer | KRAS G13D | DLD1 | Colon cancer |
| MCF7 | Breast cancer | KRAS G61H | NCI-H460 | Lung cancer | |
| GPC3 high expression | Hep G2 | Liver cancer | KRAS G12V | NCI-H441 | Pancreatic cancer |
| Hep3B | Liver cancer | Capan 2 | Pancreatic cancer | ||
| Huh-7 | Liver cancer | PANC 03.27 | Pancreatic cancer | ||
| GPC3 no expression | SK-HEP-1 | Liver cancer | SW620 | Colon cancer | |
| MET amplification | EBC-1 | Lung squamous | BRAF V600E | HT29 | Colon cancer |
| Hs746T | Gastric cancer | Colo 205 | Colon cancer | ||
| H1993 | NSCLC | Colo 741 | Rectal cancer | ||
| MET exon 14 skipping | H596 | Lung squamous | CDH6 high expression | 143B | Osteosarcoma |
| KRAS G12D | Panc-1 | Pancreatic cancer | U-2 OS | Osteosarcoma | |
| GP2D | Colon cancer | EFO-21 | Ovarian cancer | ||
| SK-LU-1 | Lung adenocarcinoma | NCI-N87 | Gastric cancer | ||
| Aspc-1 | Metastatic pancreatic | FRa high expression | SK-OV-3 | Ovarian cancer | |
| SW1990 | Pancreatic cancer | TOV-21G | Ovarian cancer | ||
| panc10.05 | Pancreatic cancer | GPR20 | EFO-21 | Ovarian cancer |
Table: LIDE cell lines with high profile expression targets